An appraisal of Cellsonic Regeneration

Medical Shockwaves for healing all Skin Ulcers

Medical Disclaimer: This information is for educational purposes only. Always consult qualified healthcare providers before making treatment decisions.

Declaration

Our clinical evaluation utilized CellSonic Regeneration equipment without financial involvement in the manufacturing company, CellSonic Regeneration. This assessment maintains complete independence for objective medical analysis.

Summary

Medical shockwave therapy demonstrates significant potential in treating skin ulcerations regardless of the underlying etiology (cause). This non-invasive therapeutic approach functions independently of pharmaceutical interventions, and drugs are not required. The same technological platform serves multiple medical applications, including calcification fragmentation, renal stone destruction (lithotripsy), bone tissue regeneration, and rehabilitation of sports injuries.

Patient preparation follows standard medical protocols, similar to those for any other treatment method, while the actual treatment duration spans only several minutes. The technical skill requirements remain minimal, enabling qualified nursing staff to perform procedures after appropriate training. This accessibility proves particularly valuable in developing countries and resource-limited healthcare settings where infectious disease-related ulcerations can receive treatment from locally trained medical personnel speaking the patient's language, especially beneficial for children suffering from Buruli ulcer, where traditional antimicrobial therapy shows declining effectiveness and drugs are losing the battle.

Medical Shockwaves

Shockwaves are pressure waves that propagate rapidly through biological tissues to create controlled mechanical disruption or therapeutic stimulation. These waves originate from electrohydraulic discharge, where high-voltage electrical energy creates pressure changes between electrodes within a conductive medium. Resulting acoustic waves undergo focusing through parabolic reflectors, directing energy into target tissues while maintaining transmission through aqueous (water-based) coupling media.

The critical characteristic involves rapid pressure amplitude increase measured in decibels, with optimal generation through high-voltage electrode gap discharge. This mirrors natural lightning formation, where acoustic manifestation becomes thunder.

Often parallel wave heads (described as infinity) treat wounds, while focused configurations like 5mm or 20mm provide precise targeting when concentration and limited penetration are required. Shocks generate at four per second. ESWT (Extracorporeal Shock Wave Therapy) applies to all non-invasive shockwave applications, from breaking kidney stones to healing ulcers. "Lithotripter" increasingly refers to kidney stone machines, while ESWT designates handheld devices addressed in this evaluation.

Application on skin ulcers

All skin ulcer classifications respond to treatment. The protocol begins with thorough wound debridement (dead tissue removal) and cleansing. Sterile ultrasound gel fills the wound cavity, followed by barrier film application with additional gel layering, ensuring optimal acoustic transmission from the treatment head to subdermal tissues where healing initiates. Any air pockets completely obstruct the propagation of sound waves.

The handheld applicator remains positioned within the coupling gel, directed into wound beds while moving systematically during four-pulse-per-second delivery. These pressure waves target wound interiors and surrounding margins.

This mechanically destroys pathogenic microorganisms, including viruses, bacteria, and parasites, through acoustic cavitation and direct cellular membrane disruption. Nitric oxide formation beneath wound tissues provides additional antimicrobial activity.

Vascularization improves, delivering additional blood cells. Rat skin flap trials have proved that healing on uninfected wounds is quicker with shockwaves than without. The protocol with electromagnetic machines requires 100 pulses for each square centimeter of the wound. The number of treatments required varies from one for a superficial wound to a sequence of sessions for big wounds.

Grades of ulcers

All ulcers may be treated. All infection is killed. No antibiotics are needed. However, doctors may administer drugs when suspecting infection spread beyond the wound sites. Not using antibiotics allows patients to derive full nutrition from food needed for tissue rebuilding. Microorganism resistance, including mycoplasma, becomes irrelevant because mechanical shockwave destruction physically ruptures pathogens rather than relying on biochemical mechanisms.

Shockwaves are compatible with existing wound healing methods. Diabetic foot patient advice about lifestyle, smoking, and diet still applies.

Type of ulcers

Arterial (ischemic ulcer) - inadequate arterial supply causing tissue death

Venous/varicose veins - venous insufficiency and blood pooling

Neurotropic (Diabetic) - peripheral nerve damage preventing sensation

Traumatic wounds - including burns and mechanical damage

Infected ulcer (viral, bacterial, fungal, parasite) e.g. chronic TB, Leprosy, Buruli

Inflammatory ulcer - autoimmune conditions, lupus

Tumour - benign and malignant tissue breakdown

Grades of skin ulcer

For simplicity we grade ulcers into 3 groups:

1. Pre ulceration - redness, swollen, blisters
2. Ulceration - skin gone revealing underlying tissue
3. Complicated - with extension and/or gangrene (tissue death)

The most common ulcer is vascular. Shockwaves enhance vascularisation of small arteries and arterioles to stimulate healing. It disables and kills bacteria which are the worst enemy for healing.

Our main work focuses on diabetic ulcers with advantages of cost savings for patients and health services, less patient attendance for traditional treatments, patient comfort, and as ulcers heal patients become more mobile and return to work.

Blocking shockwaves

Care must be taken when cleaning the wound to remove all old, flaky tissue under which there could be an air pocket when gel is applied. That pocket of air will block shockwaves; they cannot pass through any gas.

The trick in research is for the placebo patient to not have gel applied. They hear the bangs and think they are receiving shocks but in fact they are not because the shocks cannot travel without the aqueous medium. This same method can be used, for example, to stop shockwaves hitting the intestines and lungs where they may cause damage. On the limbs there are no risks; it is on the torso and head where care has to be taken. In the case of a child with a lot of the torso affected by Buruli ulcer and with no layer of insulating fat, the shockwaves have to hit the bacteria and go under the wound but no further. 

Future

Leading European physicians advocate for the use of shockwave therapy in emergency care settings to assist in the early treatment of soft tissue injuries and wound healing. According to a study published in Plastic and Reconstructive Surgery (Lienemann et al., 2017), extracorporeal shockwave therapy (ESWT) can be safely applied before, during, or after surgical procedures in plastic and reconstructive surgery. The research highlights that initiating shockwave therapy on wounds prior to surgery may accelerate tissue regeneration, reduce inflammation, and improve overall outcomes.

This growing body of evidence supports the potential role of ESWT in pre-theatre wound management, particularly in trauma and casualty departments. However, clinical guidelines and training are essential, and further integration into hospital protocols depends on broader regulatory and institutional acceptance.

In military situations, earlier shockwave application is better because there's no knowing whether germs are deliberately deployed by enemies, and whatever they may be, shockwaves will stop them before traveling further into bodies.

Since the 1980's, when shockwaves broke kidney stones, there was no effect on blood. Certainly, no side effects in that application.

Research now examines shockwave effects on blood cells, aiming to clean blood of infections, leaving it safe for transfusions. This follows the removal of blood infections in bodies, potentially enabling immune systems to be released from overload and combat Hepatitis, malaria, and potentially HIV. The likely outcome will be a combination therapy as shockwaves are now a non-invasive, drug-free, no-side-effect healing means.

Important Medical Notice: This evaluation provides educational information only. All medical decisions require consultation with qualified healthcare providers familiar with individual patient conditions and medical histories.